Vol. 9, Issue 3, Part A (2024)

Author(s): Sonam Bhatt, Bhoomika Sirsant, Ravi Shankar Kr Mandal, Raguvaran R, DB Mondal, Arvind Kumar Das, Anil Kumar, Ajit Kumar and Sanjay Kumar Bharti

Abstract: Canine babesiosis is a tick-borne disease caused by the parasite of the genus Babesia. It is mainly transmitted by ticks. The major complications. Of babesiosis in dogs are hepatic failure, kidney failure, DIC, oxidative damage to red blood cells, and immune-mediated hemolyticanemia. Oxidative stress can cause lipid peroxidation and erythrocyte injury in affected dogs. Clinical symptoms are usually associated with hemolysis caused by the organisms in the erythrocytes; however, anemia may also be accompanied by an inflammatory response or an immune-mediated component. In this review, we discuss the clinical signs, clinical biomarkers, diagnosis, and treatment of the disease with specific therapy along with the use of antioxidants like N-acetyl cysteine and Coenzyme Q10 for the therapeutic management of babesiosis in dogs.